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Mini-Reviews in Medicinal Chemistry

Editor-in-Chief

ISSN (Print): 1389-5575
ISSN (Online): 1875-5607

Towards Alzheimers Disease Vaccination

Author(s): Beka Solomon

Volume 2, Issue 1, 2002

Page: [85 - 92] Pages: 8

DOI: 10.2174/1389557023406575

Price: $65

Abstract

Active and passive immunization against fibrillar β-amyloid of various mice models of Alzheimers disease leads to the disaggregation and inhibition of plaque formation. Preliminary results showing improved behaviour and memory function obtained after administration of anti-β-amyloid vaccines to transgenic mice encourage these and related approaches for testing in the treatment and prevention of Alzheimers disease.

Keywords: Alzheimers Disease, EFRH-phage, Poly-L-lysine


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