周围细胞在神经血管单位中的作用：强调中风

Title:The Role of Pericytes in Neurovascular Unit: Emphasis on Stroke

Volume: 18 Issue: 12

关键词: 中风，蛛网膜下腔出血，周细胞，无回流，神经血管单位。

摘要: Background: Among the central nervous system (CNS) disorders, diseases like ischemic and hemorrhagic stroke which are important health care problems as well as leading causes for emergency admissions, primarily affect neurovascular structure. Despite their high rate of mortality and morbidity, very few efficient treatment targets have been established until now. Objective: Blood-brain barrier (BBB) is the mostly effected structure in stroke as detected in both clinical studies and experimental settings. BBB is composed of endothelia, astrocyte end-foot, pericytes and basal lamina. Neurovascular unit, pericytes and BBB forming endothelia play significant pathophysiological roles in both ischemic and hemorrhagic stroke.

Cite this article as:

The Role of Pericytes in Neurovascular Unit: Emphasis on Stroke, Current Drug Targets 2017; 18 (12) . https://dx.doi.org/10.2174/1389450117666160613104523