摘要
老年痴呆症患者常见痴呆的行为和精神症状(BPSD)。BPSD对病人和照顾者有着重大的影响。关于BPSD治疗的药理学方法可用的文献是稀少的,有时呈现不一致的结果。没有FDA批准用于BPSD治疗的药物,老年人群痴呆可用药物的使用与明显的副作用有关。此文概述了BPSD的评估,探讨了药物管理的总则,并审查了目前非药物和药物治疗策略以及相关风险的证据。
关键词: 阿尔茨海默病,焦虑,痴呆的行为和心理症状,老年痴呆症,抑郁,治疗。
Current Alzheimer Research
Title:The Treatment of Behavioral and Psychological Symptoms of Dementia: Weighing Benefits and Risks
Volume: 13 Issue: 10
Author(s): Kristina F. Zdanys, André F. Carvalho, Rajesh R. Tampi, David C. Steffens
Affiliation:
关键词: 阿尔茨海默病,焦虑,痴呆的行为和心理症状,老年痴呆症,抑郁,治疗。
摘要: Behavioral and psychological symptoms of dementia (BPSD) are common among patients with dementia. BPSD have significant implications on outcomes for patients and caregivers. Available literature for pharmacological approaches to BPSD is sparse and at times inconsistent. There are no FDA-approved medications for the management of BPSD, and the use of available medications is associated with significant adverse effects among aged populations with dementia. This review outlines the assessment of BPSD, discusses general principles of management, and examines current evidence for non-pharmacologic and pharmacologic treatment strategies as well as associated risks.
Export Options
About this article
Cite this article as:
Kristina F. Zdanys, André F. Carvalho, Rajesh R. Tampi, David C. Steffens , The Treatment of Behavioral and Psychological Symptoms of Dementia: Weighing Benefits and Risks, Current Alzheimer Research 2016; 13 (10) . https://dx.doi.org/10.2174/1567205013666160510121633
DOI https://dx.doi.org/10.2174/1567205013666160510121633 |
Print ISSN 1567-2050 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5828 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Ketogenic Diets in the Treatment of Epilepsy
Current Pharmaceutical Design Microglial dependent protective effects of neuroactive steroids
CNS & Neurological Disorders - Drug Targets The Innate Immunity in Alzheimer Disease- Relevance to Pathogenesis and Therapy
Current Pharmaceutical Design Recent Advances in Nanotechnology-Based Drug Delivery Approaches for Alzheimer disease
Current Drug Targets Prediction of Comparative Inhibition Efficiency for a Novel Natural Ligand, Galangin Against Human Brain Acetylcholinesterase, Butyrylcholinesterase and 5-Lipoxygenase: A Neuroinformatics Study
CNS & Neurological Disorders - Drug Targets Overview and Findings from the Religious Orders Study
Current Alzheimer Research Identification of Human Acetylcholinesterase Inhibitors from the Constituents of EGb761 by Modeling Docking and Molecular Dynamics Simulations
Combinatorial Chemistry & High Throughput Screening Bone Loss and Osteoporosis are Associated with Conversion from Mild Cognitive Impairment to Alzheimer’s Disease
Current Alzheimer Research Natural Product Formulations for the Prevention and Treatment of Alzheimer's disease: A Patent Review
Recent Patents on Drug Delivery & Formulation Neuroprotective Effects of Lithium in Patients with Bipolar Disorder
Current Psychopharmacology Genetic and Environmental Modifiers of Alzheimers Disease Phenotypes in the Mouse
Current Alzheimer Research Snapshots of Protein Folding Problem: Implications of Folding and Misfolding Studies
Protein & Peptide Letters GSK-3 Inhibitors: Recent Developments and Therapeutic Potential
Current Signal Transduction Therapy An Anti-apoE4 Specific Monoclonal Antibody Counteracts the Pathological Effects of apoE4 In Vivo
Current Alzheimer Research A Review of Dietary Influences on Cardiovascular Health: Part 1: the role of Dietary Nutrients
Cardiovascular & Hematological Disorders-Drug Targets The Emergent Cardiovascular Risk Factors and Organ Damage in Arterial Hypertension
Current Hypertension Reviews The Indiana Alzheimer Disease Centers Symposium on Mild Cognitive Impairment. Cognitive Training in Older Adults: Lessons from the ACTIVE Study
Current Alzheimer Research Emerging Risk Factors for Cerebrovascular Disease
Current Drug Targets Study of Oxidized Lipids as Endogenous Substrates of P-gp (ABCB1)
Drug Metabolism Letters Nuclear Medicine: Proof of Principle for Targeted Drugs in Diagnosis and Therapy
Current Pharmaceutical Design