Abstract
In the recent few years, the emergence of heterocyclic ring-containing anti-cancer agents has gained a great deal of attention among medicinal chemists. Among these, azepine-based compounds are particularly becoming attractive recently. In this Focus Review, we highlight the recent advancements in the development of azepine-based anti-cancer compounds since the year 2000.
Keywords: Anticancer agents, azepane scaffold, chemotherapeutics, histone deacetylases, kinase inhibitors, tubulin inhibitors, phototherapeutic agents, hormone modulators.
Graphical Abstract
Anti-Cancer Agents in Medicinal Chemistry
Title: Recent Advances in Anticancer Chemotherapeutics based upon Azepine Scaffold
Volume: 16 Issue: 5
Author(s): Sarbjit Singh, Jail Goo, Veeraswamy Gajulapati, Tong-Shin Chang, Kyeong Lee and Yongseok Choi
Affiliation:
Keywords: Anticancer agents, azepane scaffold, chemotherapeutics, histone deacetylases, kinase inhibitors, tubulin inhibitors, phototherapeutic agents, hormone modulators.
Abstract: In the recent few years, the emergence of heterocyclic ring-containing anti-cancer agents has gained a great deal of attention among medicinal chemists. Among these, azepine-based compounds are particularly becoming attractive recently. In this Focus Review, we highlight the recent advancements in the development of azepine-based anti-cancer compounds since the year 2000.
Export Options
About this article
Cite this article as:
Singh Sarbjit, Goo Jail, Gajulapati Veeraswamy, Chang Tong-Shin, Lee Kyeong and Choi Yongseok, Recent Advances in Anticancer Chemotherapeutics based upon Azepine Scaffold , Anti-Cancer Agents in Medicinal Chemistry 2016; 16 (5) . https://dx.doi.org/10.2174/1871520615666150916091750
DOI https://dx.doi.org/10.2174/1871520615666150916091750 |
Print ISSN 1871-5206 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5992 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Various Novel Erythromycin Derivatives Obtained by Different Modifications: Recent Advance in Macrolide Antibiotics
Mini-Reviews in Medicinal Chemistry 4-Aminoquinazoline Analogs: A Novel Class of Anticancer Agents
Mini-Reviews in Medicinal Chemistry Determination of the Percent Composition and Mineral Content of the Leaves of the Insulin Plant (Cissus sicyoides) with the Goal of Including it in the Usual Diet
The Natural Products Journal A Mechanistic Study on Altered Pharmacokinetics of Irinotecan by St. Johns Wort
Current Drug Metabolism In vitro Study on the Effect of Nanoparticles and Transfersomes as Targeted Drug Carrier for Cancer
Nanoscience & Nanotechnology-Asia MicroRNA-21: From Cancer to Cardiovascular Disease
Current Drug Targets Bio-AIMS Collection of Chemoinformatics Web Tools based on Molecular Graph Information and Artificial Intelligence Models
Combinatorial Chemistry & High Throughput Screening Cathelicidins: Peptides with Antimicrobial, Immunomodulatory, Anti- Inflammatory, Angiogenic, Anticancer and Procancer Activities
Current Protein & Peptide Science Pannexin Channels: The Emerging Therapeutic Targets
Current Drug Targets Recent Advances in Substrate Identification of Protein Kinases in Plants and Their Role in Stress Management
Current Genomics Recent Therapeutic Advances for Treating Medulloblastoma: Focus on New Molecular Targets
CNS & Neurological Disorders - Drug Targets Access to Opioids for Patients with Advanced Disease
Current Pharmaceutical Design Natural New Sesquiterpenes: Structural Diversity and Bioactivity
Current Organic Chemistry Update on Screening in Prostate Cancer Based on Recent Clinical Trials
Reviews on Recent Clinical Trials Nanobiotechnological Approaches to Overcome Drug Resistance in Breast Cancer
Current Cancer Drug Targets Drug Delivery Systems with Modified Release for Systemic and Biophase Bioavailability
Current Clinical Pharmacology The Membrane-targeted Alkylphosphocholine Erufosine Interferes with Survival Signals from the Extracellular Matrix
Anti-Cancer Agents in Medicinal Chemistry Mitogenomics: Recognizing the Significance of Mitochondrial Genomic Variation for Personalized Medicine
Current Pharmacogenomics and Personalized Medicine Gold Nanoparticles Enhance the Toluidine Blue-Induced Lethal Photosensitisation of Staphylococcus aureus
Current Nanoscience Antiaging Therapy: A Novel Target for Antilipolytic Drugs
Mini-Reviews in Medicinal Chemistry