Abstract
Sesquiterpenoids, consist of 15 carbons backbone, may play a highly significant role in natural products. There are various types of the sesquiterpenoids due to different spatial configurations via modification and rearrangement. Sesquiterpenoids exhibit various biological activities: anti-tumor, anti-viral, anti-microbial, anti-inflammatory and so on. The study on sesquiterpenes may receive more and more attentions, and will increase the chance to discover bio-active drug leads with medicinal potential. The present paper reviews the latest progress in the structural diversity and the biological activity of the new sesquiterpenes isolated from natural resource in recent years. Overall, 337 compounds, and 201 references are presented.
Keywords: Sesquiterpenoids, structure, biological activities.
Graphical Abstract
Current Organic Chemistry
Title:Natural New Sesquiterpenes: Structural Diversity and Bioactivity
Volume: 20 Issue: 9
Author(s): Dan Li and Kui-Wu Wang
Affiliation:
Keywords: Sesquiterpenoids, structure, biological activities.
Abstract: Sesquiterpenoids, consist of 15 carbons backbone, may play a highly significant role in natural products. There are various types of the sesquiterpenoids due to different spatial configurations via modification and rearrangement. Sesquiterpenoids exhibit various biological activities: anti-tumor, anti-viral, anti-microbial, anti-inflammatory and so on. The study on sesquiterpenes may receive more and more attentions, and will increase the chance to discover bio-active drug leads with medicinal potential. The present paper reviews the latest progress in the structural diversity and the biological activity of the new sesquiterpenes isolated from natural resource in recent years. Overall, 337 compounds, and 201 references are presented.
Export Options
About this article
Cite this article as:
Li Dan and Wang Kui-Wu, Natural New Sesquiterpenes: Structural Diversity and Bioactivity, Current Organic Chemistry 2016; 20 (9) . https://dx.doi.org/10.2174/1385272819666151008014405
DOI https://dx.doi.org/10.2174/1385272819666151008014405 |
Print ISSN 1385-2728 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5348 |
Call for Papers in Thematic Issues
Catalytic C-H bond activation as a tool for functionalization of heterocycles
The major topic is the functionalization of heterocycles through catalyzed C-H bond activation. The strategies based on C-H activation not only provide straightforward formation of C-C or C-X bonds but, more importantly, allow for the avoidance of pre-functionalization of one or two of the cross-coupling partners. The beneficial impact of ...read more
Related Journals
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Oncogenic Fusion Tyrosine Kinases as Molecular Targets for Anti-Cancer Therapy
Anti-Cancer Agents in Medicinal Chemistry Epigallocatechin-3-gallate Increases RXRγ-mediated Pro-apoptotic and Anti-invasive Effects in Gastrointestinal Cancer Cell Lines
Current Cancer Drug Targets A Novel Method for Screening of Anti-Cancer Drugs: Availability of Screening in Acidic Medium
Recent Patents on Biomedical Engineering (Discontinued) Relative In Vitro Potentials of Parthenolide to Induce Apoptosis and Cell Cycle Arrest in Skin Cancer Cells
Current Drug Discovery Technologies Role of Rap2 and its Downstream Effectors in Tumorigenesis
Anti-Cancer Agents in Medicinal Chemistry Recent Advances in Heterocyclic Tubulin Inhibitors Targeting the Colchicine Binding Site
Anti-Cancer Agents in Medicinal Chemistry Double Layered Hydroxides as Potential Anti-Cancer Drug Delivery Agents
Mini-Reviews in Medicinal Chemistry Context-dependent Action of Transforming Growth Factor β Family Members on Normal and Cancer Stem Cells
Current Pharmaceutical Design The Promise of miRNA Replacement Therapy for Hepatocellular Carcinoma
Current Gene Therapy Ligand Binding Domain of Vitamin D Receptors
Current Topics in Medicinal Chemistry Exosomal miR-214-5p Released from Glioblastoma Cells Modulates Inflammatory Response of Microglia after Lipopolysaccharide Stimulation through Targeting CXCR5
CNS & Neurological Disorders - Drug Targets Damage and Recovery of the Bone Marrow Microenvironment Induced by Cancer Chemotherapy – Potential Regulatory Role of Chemokine CXCL12/Receptor CXCR4 Signalling
Current Molecular Medicine Probing Gallic Acid for Its Broad Spectrum Applications
Mini-Reviews in Medicinal Chemistry Idronoxil as an Anticancer Agent: Activity and Mechanisms
Current Cancer Drug Targets Autophagy: Molecular Mechanisms and their Implications for Anticancer Therapies
Current Cancer Drug Targets Potentiation of Anti-Cancer Treatment by Modulators of Energy Metabolism
Current Pharmaceutical Biotechnology Chemical Constituents and Antitumor Mechanisms of <i>Artemisia</i>
Anti-Cancer Agents in Medicinal Chemistry Effects of Agaricus Blazei Extract Plus Lactoferrin or Lactoferrin Alone on Tumor Growth and UFT-Induced Adverse Reactions in Sarcoma 180- or Highly Metastatic Osteosarcoma LM8-Bearing Mice
The Natural Products Journal The Insulin-Like Growth Factor (IGF) Signaling Pathway: Strategies for Successful Therapeutic Tasks in Cancer Treatment
Current Cancer Therapy Reviews Recent Developments in the Synthesis and Biological Activity of Muramylpeptides
Current Medicinal Chemistry