Abstract
Sesquiterpenoids, consist of 15 carbons backbone, may play a highly significant role in natural products. There are various types of the sesquiterpenoids due to different spatial configurations via modification and rearrangement. Sesquiterpenoids exhibit various biological activities: anti-tumor, anti-viral, anti-microbial, anti-inflammatory and so on. The study on sesquiterpenes may receive more and more attentions, and will increase the chance to discover bio-active drug leads with medicinal potential. The present paper reviews the latest progress in the structural diversity and the biological activity of the new sesquiterpenes isolated from natural resource in recent years. Overall, 337 compounds, and 201 references are presented.
Keywords: Sesquiterpenoids, structure, biological activities.
Graphical Abstract
Current Organic Chemistry
Title:Natural New Sesquiterpenes: Structural Diversity and Bioactivity
Volume: 20 Issue: 9
Author(s): Dan Li and Kui-Wu Wang
Affiliation:
Keywords: Sesquiterpenoids, structure, biological activities.
Abstract: Sesquiterpenoids, consist of 15 carbons backbone, may play a highly significant role in natural products. There are various types of the sesquiterpenoids due to different spatial configurations via modification and rearrangement. Sesquiterpenoids exhibit various biological activities: anti-tumor, anti-viral, anti-microbial, anti-inflammatory and so on. The study on sesquiterpenes may receive more and more attentions, and will increase the chance to discover bio-active drug leads with medicinal potential. The present paper reviews the latest progress in the structural diversity and the biological activity of the new sesquiterpenes isolated from natural resource in recent years. Overall, 337 compounds, and 201 references are presented.
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Cite this article as:
Li Dan and Wang Kui-Wu, Natural New Sesquiterpenes: Structural Diversity and Bioactivity, Current Organic Chemistry 2016; 20 (9) . https://dx.doi.org/10.2174/1385272819666151008014405
DOI https://dx.doi.org/10.2174/1385272819666151008014405 |
Print ISSN 1385-2728 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5348 |
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Catalytic C-H bond activation as a tool for functionalization of heterocycles
The major topic is the functionalization of heterocycles through catalyzed C-H bond activation. The strategies based on C-H activation not only provide straightforward formation of C-C or C-X bonds but, more importantly, allow for the avoidance of pre-functionalization of one or two of the cross-coupling partners. The beneficial impact of ...read more
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