摘要
性别差异已报道了传统的血管危险因素如吸烟,肥胖,糖尿病,高血压,血脂异常,年龄和过早冠状动脉心脏疾病的家族史。患病率,严 重程度,协助和对治疗的反应若干新兴心血管疾病(CVD)的危险因素,也可能男女之间不同。这样的心血管病危险因素包括某些炎症和 凝血标志物,内皮功能障碍,同型半胱氨酸,血脂紊乱,微量白蛋白尿/蛋白尿,冠脉钙化积分,动脉硬化,牙周炎,炎性肠综合征,阻塞 性睡眠呼吸暂停,糖代谢障碍,代谢综合征和非酒精性脂肪肝疾病。另外还需要更大样本的前瞻性研究来确定这些关系)。激素替代疗法可 能也会影响血管风险。这些数据在评估和处理妇女心血管疾病的风险应被考虑。
关键词: 动脉硬化,炎症标志物,代谢综合症,不含酒精的脂肪肝疾病,血管的危险因素,妇女
Current Medicinal Chemistry
Title:Emerging Vascular Risk Factors in Women: Any Differences from Men?
Volume: 22 Issue: 31
Author(s): N. Katsiki and D. P. Mikhailidis
Affiliation:
关键词: 动脉硬化,炎症标志物,代谢综合症,不含酒精的脂肪肝疾病,血管的危险因素,妇女
摘要: Gender differences have been reported for traditional vascular risk factors such as smoking, obesity, diabetes, hypertension, dyslipidemia, age and family history of premature coronary heart disease. The prevalence, severity, associations and response to treatment of several emerging cardiovascular disease (CVD) risk factors may also differ between men and women. Such CVD risk factors include certain inflammatory and hemostatic markers, endothelial dysfunction, homocysteine, lipid disorders, microalbuminuria/proteinuria, coronary artery calcium score, arterial stiffness, periodontitis, inflammatory bowel syndrome, obstructive sleep apnea, impaired glucose metabolism, metabolic syndrome and non-alcoholic fatty liver disease. Further larger prospective studies are needed to establish these relationships. Hormone replacement therapy may also affect vascular risk. These data should be taken into consideration when assessing and treating CVD risk in women.
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Cite this article as:
N. Katsiki and D. P. Mikhailidis , Emerging Vascular Risk Factors in Women: Any Differences from Men?, Current Medicinal Chemistry 2015; 22 (31) . https://dx.doi.org/10.2174/0929867322666150904110053
DOI https://dx.doi.org/10.2174/0929867322666150904110053 |
Print ISSN 0929-8673 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-533X |
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