摘要
研究表明,阿尔茨海默病患者对自相关信息情绪的影响是有益的。本文研究了情绪是否能提升目的记忆(例如:我跟你讲过这手稿吗?),这被认为是自相关的(例如:我跟你讲过这手稿吗?)。出于此目的,27名AD患者和30名健康的老年人讲述24个中立的事实与8张中性、8张积极和8张消极的面容相对应。在随后的识别任务中,参与者必须决定他们是否已经将一个给定的事实与一个给定的面容相对应。数据表明,AD患者情绪对目的地记忆没有影响。然而,相对于积极的面容来说,健康的老年人对消极面容有着更好的目的记忆,并且之后的记忆优于中性面容。就这种记忆在AD患者中大幅下降来说,患者情绪对目的地记忆没有影响得到了解释。
关键词: 阿尔茨海默氏病,目的地记忆,情绪,情节记忆。
Current Alzheimer Research
Title:Emotion and Destination Memory in Alzheimer’s Disease
Volume: 12 Issue: 8
关键词: 阿尔茨海默氏病,目的地记忆,情绪,情节记忆。
摘要: Research shows beneficial effect of emotion on self-related information in patients with Alzheimer’s Disease (AD). Our paper investigates whether emotion improves destination memory (e.g., did I tell you about the manuscript?), which is thought to be self-related (e.g., did I tell you about the manuscript?). To this aim, twenty-seven AD patients and thirty healthy older adults told 24 neutral facts to eight neutral faces, eight positive faces, and eight negative faces. On a subsequent recognition task, participants had to decide whether they had previously told a given fact to a given face or not. Data revealed no emotional effect on destination memory in AD patients. However, in healthy older adults, better destination memory was observed for negative faces than for positive faces, and the latter memory was better than for neutral faces. The absence of emotional effect on destination memory in AD is interpreted in terms of substantial decline in this memory in the disease.
Export Options
About this article
Cite this article as:
Emotion and Destination Memory in Alzheimer’s Disease, Current Alzheimer Research 2015; 12 (8) . https://dx.doi.org/10.2174/1567205012666150710112802
DOI https://dx.doi.org/10.2174/1567205012666150710112802 |
Print ISSN 1567-2050 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5828 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Editorial (Thematic Issue: Effective and Promising Treatments for Neurological Disorders and Cancer)
Current Pharmaceutical Design Assessment of Memory Impairment in Early Diagnosis of Alzheimer’s Disease
Current Alzheimer Research A Multi-layered Variable Selection Strategy for QSAR Modeling of Butyrylcholinesterase Inhibitors
Current Topics in Medicinal Chemistry Electroencephalography and Dementia: A Literature Review and Future Perspectives
CNS & Neurological Disorders - Drug Targets Editorial [Hot topic: Endocannabinoid Signaling and Neuroinflammatory Diseases (Executive Editor: Mauro Maccarrone)]
Current Pharmaceutical Design Segmentation of Brain MRI for Detecting Alzheimer's Disease
Current Medical Imaging Novel Therapeutic Strategies in Major Depression: Focus on RNAi and Ketamine
Current Pharmaceutical Design Statins, Risk of Death and Ischemic Stroke in Patients with Dementia: A Registry-Based Observational Cohort Study
Current Alzheimer Research Detecting Non-cognitive Features of Prodromal Neurodegenerative Diseases
Current Aging Science Inflammation and Mood Disorders: Proinflammatory Cytokines and the Pathogenesis of Depression
Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry Discovery of MAO-B Inhibitors - Present Status and Future Directions Part I: Oxygen Heterocycles and Analogs
Mini-Reviews in Medicinal Chemistry p38 MAP Kinase Inhibitors as Potential Therapeutic Drugs for Neural Diseases
Central Nervous System Agents in Medicinal Chemistry Molecular Dynamics Simulations of Intrinsically Disordered Proteins in Human Diseases
Current Computer-Aided Drug Design Expanding the Therapeutic Potential of Statins by Means of Nanotechnology Enabled Drug Delivery Systems
Current Topics in Medicinal Chemistry Nanomedicines for Brain Targeting: A Patent Review
Recent Patents on Nanomedicine Indole Alkaloids and Semisynthetic Indole Derivatives as Multifunctional Scaffolds Aiming the Inhibition of Enzymes Related to Neurodegenerative Diseases – A Focus on Psychotria L. Genus
Current Topics in Medicinal Chemistry The Effects of Cognitive Speed of Processing Training Among Older Adults with Psychometrically- Defined Mild Cognitive Impairment
Current Alzheimer Research Models to Study Atherosclerosis: A Mechanistic Insight
Current Vascular Pharmacology A Dual Mechanism Linking NGF/proNGF Imbalance and Early Inflammation to Alzheimer's Disease Neurodegeneration in the AD11 Anti-NGF Mouse Model
CNS & Neurological Disorders - Drug Targets Concurrent Use of Antiretrovirals and Anticonvulsants in Human Immunodeficiency Virus (HIV) Seropositive Patients
Current Pharmaceutical Design