A System Review of Anti-fibrogenesis Effects of Compounds Derived from Chinese Herbal Medicine

Title:A System Review of Anti-fibrogenesis Effects of Compounds Derived from Chinese Herbal Medicine

Volume: 16 Issue: 2

Author(s): Yanling Zhao, Xiao Ma, Jiabo Wang, Xuan He, Yaming Zhang, Ye Wang, Honghong Liu, Honghui Shen and Xiaohe Xiao

Affiliation:

Keywords: Chinese herbal medicine, Extracellular matrix, Hepatic stellate cell, Liver fibrosis.

Abstract: Chinese herbal medicine (CHM), an alternative and complementary medicine, has been applied in various diseases. Recently, a number of anti-liver fibrogenesis compounds exhibiting antiliver fibrosis effects have been discovered in CHM. In this review, we reviewed the published data on their anti-fibrosis effects and discussed the possible underlying mechanisms. More investigations are needed to improve the insight into therapeutic effect of CHM on liver fibrosis.

Cite this article as:

Zhao Yanling, Ma Xiao, Wang Jiabo, He Xuan, Zhang Yaming, Wang Ye, Liu Honghong, Shen Honghui and Xiao Xiaohe, A System Review of Anti-fibrogenesis Effects of Compounds Derived from Chinese Herbal Medicine, Mini-Reviews in Medicinal Chemistry 2016; 16 (2) . https://dx.doi.org/10.2174/1389557515666150709121908