Oligonucleotides and Oligonucleotide Conjugates: A New Approach for Cancer Treatment

Title: Oligonucleotides and Oligonucleotide Conjugates: A New Approach for Cancer Treatment

Volume: 12 Issue: 1

Author(s): Tatiana Da Ros, Giampiero Spalluto, Maurizio Prato, Tula Saison-Behmoaras, Alexandre Boutorine and Barbara Cacciari

Affiliation:

Keywords: antisense oligonucleotides, mrna, Rnase, hybridisation, gene-directed therapy

Abstract: In this account we summarise recent studies on oligonucleotides and oligonucleotide derivatives and their utilisation in antigene, antisense and decoy approaches, with particular attention to peptide nucleic acids, locked nucleic acids and oligonucleotide conjugates, the most promising compounds in this field.

Cite this article as:

Ros Da Tatiana, Spalluto Giampiero, Prato Maurizio, Saison-Behmoaras Tula, Boutorine Alexandre and Cacciari Barbara, Oligonucleotides and Oligonucleotide Conjugates: A New Approach for Cancer Treatment, Current Medicinal Chemistry 2005; 12 (1) . https://dx.doi.org/10.2174/0929867053363603