Abstract
The rapidly expanding knowledge of the pathogenesis of a variety of forms of cancer at the molecular level is now providing new targets for drug discovery and development. This has enabled us to successfully develop rationally designed therapies for cancer patients, and the results of their clinical evaluation are now becoming available. The optimal clinical development of target-based anticancer drugs will require fundamental changes to the way trials are designed, outcome is evaluated, and patients are selected to receive therapy. A thorough knowledge of what is accomplished so far is the cornerstone to optimally develop and implement these new strategies.
Keywords: targeted therapy, egfr, her2, vegfr
Current Cancer Therapy Reviews
Title: Membrane Receptor and Antiangiogenic Targeted Therapies in the Treatment of Cancer
Volume: 1 Issue: 1
Author(s): Antonio Jimeno and Hernán Cortes-Funes
Affiliation:
Keywords: targeted therapy, egfr, her2, vegfr
Abstract: The rapidly expanding knowledge of the pathogenesis of a variety of forms of cancer at the molecular level is now providing new targets for drug discovery and development. This has enabled us to successfully develop rationally designed therapies for cancer patients, and the results of their clinical evaluation are now becoming available. The optimal clinical development of target-based anticancer drugs will require fundamental changes to the way trials are designed, outcome is evaluated, and patients are selected to receive therapy. A thorough knowledge of what is accomplished so far is the cornerstone to optimally develop and implement these new strategies.
Export Options
About this article
Cite this article as:
Jimeno Antonio and Cortes-Funes Hernán, Membrane Receptor and Antiangiogenic Targeted Therapies in the Treatment of Cancer, Current Cancer Therapy Reviews 2005; 1 (1) . https://dx.doi.org/10.2174/1573394052952519
DOI https://dx.doi.org/10.2174/1573394052952519 |
Print ISSN 1573-3947 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6301 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Bioengineered 3D Scaffolds in Cancer Research: Focus on Epithelial to Mesenchymal Transition and Drug Screening
Current Pharmaceutical Design Development, Characterization and in vivo Localization Study of Topical 5-Fluorouracil Gels: A Comparative Study with Conventional Formulation
Current Drug Delivery Association between hTERT Polymorphisms and Female Papillary Thyroid Carcinoma
Recent Patents on Anti-Cancer Drug Discovery Patent Selections:
Recent Patents on Inflammation & Allergy Drug Discovery Nutritional Status and Lipid Profile in HIV-Infected Adults
Endocrine, Metabolic & Immune Disorders - Drug Targets The Role and Impact of SNPs in Pharmacogenomics and Personalized Medicine
Current Drug Metabolism Overview of Cantharidin and its Analogues
Current Medicinal Chemistry Fine Tuning Therapeutic Targeting of the Sphingolipid Biosynthetic Pathway to Treat Atherosclerosis
Current Vascular Pharmacology A Study of the Mechanism of Binding between Neratinib and MAD2L1 Based on Molecular Simulation and Multi-spectroscopy Methods
Current Pharmaceutical Design Artificial Virus as Trump-card to Resolve Exigencies in Targeted Gene Delivery
Mini-Reviews in Medicinal Chemistry Amrubicin: A Synthetic Anthracyclin Analogue in the Treatment of Extensive Stage Small Cell Lung Cancer
Recent Patents on Anti-Cancer Drug Discovery Ganoderma lucidum: A Potential for Biotechnological Production of Anti-Cancer and Immunomodulatory Drugs
Recent Patents on Anti-Cancer Drug Discovery Isolation of a Phytase with Distinctive Characteristics from an Edible Mushroom, Pleurotus eryngii
Protein & Peptide Letters Epigenetics in Metastatic Breast Cancer: Its Regulation and Implications in Diagnosis, Prognosis and Therapeutics
Current Cancer Drug Targets Variability of Biological Activities of Limonoids Derived from Plant Sources
Mini-Reviews in Organic Chemistry Epigenetic Basis of Individual Variability to Major Psychosis
Current Pharmacogenomics and Personalized Medicine Nucleic Acids Delivery Systems: A Challenge for Pharmaceutical Technologists
Current Drug Metabolism Multiple Forms of Human DNA Polymerase Delta Sub-Assembling in Cellular DNA Transactions
Current Protein & Peptide Science Transferrin-Conjugated Nanocarriers as Active-Targeted Drug Delivery Platforms for Cancer Therapy
Current Pharmaceutical Design Hypericin - A New Antiviral and Antitumor Photosensitizer: Mechanism of Action and Interaction with Biological Macromolecules
Current Drug Targets