Role of the Epithelial Cell Rests of Malassez in Periodontal Homeostasis and Regeneration - A Review

Title:Role of the Epithelial Cell Rests of Malassez in Periodontal Homeostasis and Regeneration - A Review

Volume: 10 Issue: 5

Author(s): Zhenhua Yang, Yanjiao Li, Xiaojie Ma, Lin Shen, Zhihe Zhao and Fang Jin

Affiliation:

Keywords: Hertwig's epithelial root sheath, epithelial cell rests Malassez, periodontium development, periodontal regeneration, cementogenesis, stem cells.

Abstract: Predictable and complete periodontal regeneration following periodontitis has been the ultimate goal of periodontal treatment. It has been recognized that Hertwig’s epithelial root sheath (HERS) cells play a crucial role in cementogenesis and root formation. As the descendants of HERS and unique odontogenic epithelium in the adult periodontium, epithelial cell rests of Malassez (ERM) have long been considered as quiescent epithelial remnants devoid of structure and function. Here we will present an overview of our present understanding and putative functions of the ERM in the regeneration of periodontal tissues.

Cite this article as:

Yang Zhenhua, Li Yanjiao, Ma Xiaojie, Shen Lin, Zhao Zhihe and Jin Fang, Role of the Epithelial Cell Rests of Malassez in Periodontal Homeostasis and Regeneration - A Review, Current Stem Cell Research & Therapy 2015; 10 (5) . https://dx.doi.org/10.2174/1574888X10666150312100957