摘要
囊性纤维化是一种遗传性疾病,在很小的年龄就可致死。其特点是由呼吸感染,呼吸道阻塞,炎症反应,最终晚期肺衰竭。CF也损害胰腺外分泌功能造成严重的并发症,如营养不良。目前治疗这种多系统疾病需要药理学和营养学方法的互相合作。越来越多的证据表明,生物活性食物成分,如不饱和脂肪酸,植物化学成分及抗氧化剂,都对CF疾病的管理有积极作用。本文综述了生物活性成分在CF治疗中的研究现状。
关键词: 抗氧化,生物活性食品成分,囊性纤维化,功能性食品,营养品,多不饱和脂肪酸,植物化学成分
图形摘要
Current Drug Targets
Title:Bioactive Food Components as Dietary Intervention for Cystic Fibrosis
Volume: 16 Issue: 9
Author(s): Nualpun Sirinupong and Zhe Yang
Affiliation:
关键词: 抗氧化,生物活性食品成分,囊性纤维化,功能性食品,营养品,多不饱和脂肪酸,植物化学成分
摘要: Cystic fibrosis (CF) is a genetic disorder that can lead to death at an early age. CF is characterized by respiratory infection, airway obstruction, inflammation, and eventually end-stage lung failure. CF also damages pancreatic exocrine function resulting in serious complications such as nutritional deficiencies. Current therapy to this multisystem disease requires the practice of both pharmacological and nutritional approaches. Growing evidence shows that bioactive food components, such as polyunsaturated fatty acids, phytochemicals, and antioxidants, have beneficial effects in the management of CF disease. This review will summarize the current status of bioactive compounds in CF therapy.
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Cite this article as:
Nualpun Sirinupong and Zhe Yang , Bioactive Food Components as Dietary Intervention for Cystic Fibrosis, Current Drug Targets 2015; 16 (9) . https://dx.doi.org/10.2174/1389450115666141122211111
DOI https://dx.doi.org/10.2174/1389450115666141122211111 |
Print ISSN 1389-4501 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-5592 |
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