Abstract
Seventy five percent of hospitalized patients with Crohn’s disease suffer from malnutrition. One third of Crohn’s disease patients have a body mass index below 20. Sixty percent of Crohn’s disease patients have sarcopenia. However some inflammatory bowel disease (IBD) patients are obese or suffer from sarcopenic-obesity. IBD patients have many vitamin and nutrient deficiencies, which can lead to important consequences such as hyperhomocysteinemia, which is associated with a higher risk of thromboembolic disease. Nutritional deficiencies in IBD patients are the result of insufficient intake, malabsorption and protein-losing enteropathy as well as metabolic disturbances directly induced by the chronic disease and its treatments, in particular corticosteroids. Screening for nutritional deficiencies in chronic disease patients is warranted. Managing the deficiencies involves simple nutritional guidelines, vitamin supplements, and nutritional support in the worst cases.
Keywords: Crohn's disease, enteral nutrition, malnutrition, metabolism, nutrition, obesity, osteopenia, parenteral nutrition, sarcopenia, ulcerative colitis, vitamins.
Current Drug Targets
Title:Nutrition in Adult Patients with Inflammatory Bowel Disease
Volume: 15 Issue: 11
Author(s): Xavier Hebuterne, Jerome Filippi and Stephane M. Schneider
Affiliation:
Keywords: Crohn's disease, enteral nutrition, malnutrition, metabolism, nutrition, obesity, osteopenia, parenteral nutrition, sarcopenia, ulcerative colitis, vitamins.
Abstract: Seventy five percent of hospitalized patients with Crohn’s disease suffer from malnutrition. One third of Crohn’s disease patients have a body mass index below 20. Sixty percent of Crohn’s disease patients have sarcopenia. However some inflammatory bowel disease (IBD) patients are obese or suffer from sarcopenic-obesity. IBD patients have many vitamin and nutrient deficiencies, which can lead to important consequences such as hyperhomocysteinemia, which is associated with a higher risk of thromboembolic disease. Nutritional deficiencies in IBD patients are the result of insufficient intake, malabsorption and protein-losing enteropathy as well as metabolic disturbances directly induced by the chronic disease and its treatments, in particular corticosteroids. Screening for nutritional deficiencies in chronic disease patients is warranted. Managing the deficiencies involves simple nutritional guidelines, vitamin supplements, and nutritional support in the worst cases.
Export Options
About this article
Cite this article as:
Hebuterne Xavier, Filippi Jerome and Schneider M. Stephane, Nutrition in Adult Patients with Inflammatory Bowel Disease, Current Drug Targets 2014; 15 (11) . https://dx.doi.org/10.2174/1389450115666140930150047
DOI https://dx.doi.org/10.2174/1389450115666140930150047 |
Print ISSN 1389-4501 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-5592 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Drug Discovery in Ovarian Cancer
Recent Patents on Anti-Cancer Drug Discovery Auraptene: A Natural Biologically Active Compound with Multiple Targets
Current Drug Targets Molecular Imaging of Apoptosis In Vivo with Scintigraphic and Optical Biomarkers – A Status Report
Anti-Cancer Agents in Medicinal Chemistry Substrate Specificity, Regulation, and Polymorphism of Human Cytochrome P450 2B6
Current Drug Metabolism Physiology and Pharmacology of the Vanilloid Receptor
Current Neuropharmacology Clinical Applications and Biosafety of Human Adult Mesenchymal Stem Cells
Current Pharmaceutical Design Action and Function of Vitamin D in Digestive Tract Physiology and Pathology
Current Medicinal Chemistry MICA Gene and Relevance to Immune Responses in Organ Transplants and Inflammatory, Tumoral and Autoimmune Diseases
Current Immunology Reviews (Discontinued) Recent Knowledge and New Pharmaceutical Products in Potential Alleviation of Endometriosis
Recent Patents on Inflammation & Allergy Drug Discovery Design and Synthesis of 2-(Arylmethylideneamino) Isoindolines as New Potential Analgesic and Anti-Inflammatory Agents: A Molecular Hybridization Approach
Current Pharmaceutical Design Patent Annotations
Recent Patents on Anti-Infective Drug Discovery Studying the Human Gut Microbiota in the Trans-Omics Era - Focus on Metagenomics and Metabonomics
Current Pharmaceutical Design Vitamin D and Breast Cancer Incidence and Outcome
Anti-Cancer Agents in Medicinal Chemistry Aging and DNA Methylation
Current Chemical Biology Immunomodulatory Effects of Medicinal Plants used for Vitiligo in Traditional Persian Medicine
Current Drug Discovery Technologies The Processing of Chitosan and Its Derivatives and Their Application for Postoperative Anti-Adhesion
Mini-Reviews in Medicinal Chemistry Can We Extrapolate Data from One Immune-Mediated Inflammatory Disease to Another One?
Current Medicinal Chemistry Treatment of PSA only Recurrence of Prostate Cancer After Prior Local Therapy
Current Pharmaceutical Design Endothelin Receptor Antagonists: A New Therapeutic Option for Improving the Outcome after Solid Organ Transplantation?
Current Vascular Pharmacology Risk Factors for Prolonged Postoperative Ileus in Adult Patients Undergoing Elective Colorectal Surgery: An Observational Cohort Study
Reviews on Recent Clinical Trials