Abstract
Fatty acid-binding proteins (FABPs) are extensively expressed in animals, involved in the metabolism of fatty acids. FABPs share a much conserved secondary structure though they have 20% ~ 70% identities at the amino acid level. In addition to the role in lipid metabolism, FABPs are closely associated with cytokine production in immune cells and tumor growth and angiogenesis. Increasing studies are broadening our understanding of biological roles of FABPs beyond lipid trafficking and storage.
Keywords: Allergen, FABP4, fatty acid-binding protein, fatty acid.
Protein & Peptide Letters
Title:Fatty Acid-Binding Proteins at a Glance
Volume: 21 Issue: 6
Author(s): Yadong Zheng
Affiliation:
Keywords: Allergen, FABP4, fatty acid-binding protein, fatty acid.
Abstract: Fatty acid-binding proteins (FABPs) are extensively expressed in animals, involved in the metabolism of fatty acids. FABPs share a much conserved secondary structure though they have 20% ~ 70% identities at the amino acid level. In addition to the role in lipid metabolism, FABPs are closely associated with cytokine production in immune cells and tumor growth and angiogenesis. Increasing studies are broadening our understanding of biological roles of FABPs beyond lipid trafficking and storage.
Export Options
About this article
Cite this article as:
Zheng Yadong, Fatty Acid-Binding Proteins at a Glance, Protein & Peptide Letters 2014; 21 (6) . https://dx.doi.org/10.2174/092986652106140425124628
DOI https://dx.doi.org/10.2174/092986652106140425124628 |
Print ISSN 0929-8665 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5305 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
“Virostatics” as a Potential New Class of HIV Drugs
Current Pharmaceutical Design Isoliquiritigenin Inhibits Proliferation and Induces Apoptosis via Alleviating Hypoxia and Reducing Glycolysis in Mouse Melanoma B16F10 Cells
Recent Patents on Anti-Cancer Drug Discovery Quinoline as a Privileged Scaffold in Cancer Drug Discovery
Current Medicinal Chemistry The Redox Regulation of Thiol Dependent Signaling Pathways in Cancer
Current Pharmaceutical Design Tea and Health: Studies in Humans
Current Pharmaceutical Design Molecular and Metabolic Imaging of Castration-Resistant Prostate Cancer: State of Art and Future Prospects
Current Molecular Medicine A Review of Current Animal Models of Osteoarthritis Pain
Current Pharmaceutical Biotechnology Editorial [Hot Topic: Role of Renin-Angiotensin System (RAS) in Cancer (Guest Editor: Hiroji Uemura)]
Current Cancer Drug Targets A Brief Survey on Computational Approaches to Reveal Drug and Disease Associations
Current Drug Discovery Technologies Active Surveillance for Prostate Cancer and Small Renal Masses: New Evidences and Criticisms
Anti-Cancer Agents in Medicinal Chemistry Role of Isoprenoid Compounds on Angiogenic Regulation: Opportunities and Challenges
Current Medicinal Chemistry Plant Coumestans: Recent Advances and Future Perspectives in Cancer Therapy
Anti-Cancer Agents in Medicinal Chemistry Evaluation of the Performance of Manganese Phthalocyanines as Superoxide Dismutase Mimics
Current Analytical Chemistry Nanomedicine based on Nucleic Acids: Pharmacokinetic and Pharmacodynamic Perspectives
Current Pharmaceutical Biotechnology A Transporter Gene (Sodium Iodide Symporter) for Dual Purposes in Gene Therapy: Imaging and Therapy
Current Gene Therapy Hydroxysteroid Dehydrogenase (17β -HSD3, 17β-HSD5, and 3α-HSD3) Inhibitors:Extragonadal Regulation of Intracellular Sex Steroid Hormone Levels
Recent Patents on Endocrine, Metabolic & Immune Drug Discovery (Discontinued) Metabolic Remodeling Induced by Adipocytes: A New Achilles' Heel in Invasive Breast Cancer?
Current Medicinal Chemistry Expression and Characterisation of Recombinant Molecules in Transgenic Soybean
Current Pharmaceutical Design Computational Design, Organic Synthesis, and Biological Evaluation of Polyphenol Proteasome Inhibitors: Significance in Drug Discovery and Cancer Prevention
Drug Design Reviews - Online (Discontinued) Does the Oxazolidinone Derivatives Constitute a Functional Approach for Cancer Therapy?
Clinical Cancer Drugs