Abstract
In the present article synthesis and medicinal applications of [1, 2, 4] oxadiazoles are reviewed. The oxadiazoles have a wide range of applications such as Antitussive, Anti-inflammatory, Anaesthetic, Vasodilator, anthelmintic, antiallergic, antiplatelet effects in vitro, antithrombotic properties in vivo, etc. Many researchers have synthesized novel heterocyclic compounds containing oxadiazoles with the concept of bioisosterism.
Keywords: Anaesthetic angent, anti-inflammatory, anti-tumor agents, heterocycles, one pot synthesis, [1, 2, 4] oxadiazoles, synthetic methods.
Mini-Reviews in Medicinal Chemistry
Title:[1, 2, 4]-Oxadiazoles: Synthesis and Biological Applications
Volume: 14 Issue: 4
Author(s): Rajesh O. Bora, Bashir Dar, Vidya Pradhan and Mazahar Farooqui
Affiliation:
Keywords: Anaesthetic angent, anti-inflammatory, anti-tumor agents, heterocycles, one pot synthesis, [1, 2, 4] oxadiazoles, synthetic methods.
Abstract: In the present article synthesis and medicinal applications of [1, 2, 4] oxadiazoles are reviewed. The oxadiazoles have a wide range of applications such as Antitussive, Anti-inflammatory, Anaesthetic, Vasodilator, anthelmintic, antiallergic, antiplatelet effects in vitro, antithrombotic properties in vivo, etc. Many researchers have synthesized novel heterocyclic compounds containing oxadiazoles with the concept of bioisosterism.
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Cite this article as:
Bora O. Rajesh, Dar Bashir, Pradhan Vidya and Farooqui Mazahar, [1, 2, 4]-Oxadiazoles: Synthesis and Biological Applications, Mini-Reviews in Medicinal Chemistry 2014; 14 (4) . https://dx.doi.org/10.2174/1389557514666140329200745
DOI https://dx.doi.org/10.2174/1389557514666140329200745 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
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