A Passerini-Type Condensation: A Carboxylic Acid-Free Approach for the Synthesis of the α-Acyloxycarboxamides

Mojtaba      Mahyari; Shabnam      Shaabani; Ahmad      Shaabani; Seik   Weng   Ng

doi:10.2174/13862073113169990051

Abstract

A Passerini-type condensation for the synthesis of α-acyloxycarboxamides starting from simple and readily available inputs, including an isocyanide, aldehydes and water in the presence of trimethylsilyl azide as a catalyst under reflux conditions in toluene in good yields, is described.

Keywords: Isocyanide, Passerini reaction, α-acyloxycarboxamides.

« Previous Next »

Rights & Permissions Print Cite

Combinatorial Chemistry & High Throughput Screening

Title:A Passerini-Type Condensation: A Carboxylic Acid-Free Approach for the Synthesis of the α-Acyloxycarboxamides

Volume: 16 Issue: 10

Author(s): Mojtaba Mahyari, Shabnam Shaabani, Ahmad Shaabani and Seik Weng Ng

Affiliation:

Keywords: Isocyanide, Passerini reaction, α-acyloxycarboxamides.

Abstract: A Passerini-type condensation for the synthesis of α-acyloxycarboxamides starting from simple and readily available inputs, including an isocyanide, aldehydes and water in the presence of trimethylsilyl azide as a catalyst under reflux conditions in toluene in good yields, is described.

Export Options

Export File:

RIS (for EndNote, Reference Manager, ProCite)

BibTeX

Text

Content:

Citation Only

Citation and Abstract

About this article

Cite this article as:

Mahyari Mojtaba, Shaabani Shabnam, Shaabani Ahmad and Ng Weng Seik, A Passerini-Type Condensation: A Carboxylic Acid-Free Approach for the Synthesis of the α-Acyloxycarboxamides , Combinatorial Chemistry & High Throughput Screening 2013; 16 (10) . https://dx.doi.org/10.2174/13862073113169990051