Fungal Proteins with Antiproliferative and Anticancer Activities

T.      B. Ng; J.      H. Wong

doi:10.2174/0929866511320040007

Abstract

Fungi produce a variety of proteins with antiproliferative activity toward tumor cells and anticancer activity in tumor bearing mice. The aforementioned fungal proteins include ribonucleases, antifungal proteins, ubiquitin-like peptides, ribosome inactivating proteins, hemolysins, hemagglutinins/lectins, laccases, and protein-bound polysaccharopeptides.

Keywords: Fungi, antiproliferative, anticancer, proteins, tumor cell, ribonuclease, ribosome, hemolysin, adiotherapy, chemotherapy