Abstract
Despite progress in understanding carcinogenesis, cancer is still a major cause of morbidity and mortality worldwide. Treatment is complicated by the resistance to chemotherapeutics acquired by tumors, ability to repair damaged DNA, alteration of the interaction between drug and its target, and defects in the machinery that leads to apoptosis. The development of novel therapies based on biologically active peptides, especially antimicrobial peptides (AMPs), and proteins has emerged as a new strategy to defeat cancer.
Keywords: Anticancer peptides, anticancer proteins, antimicrobial peptides, cancer, therapy, hemotherapeutics, tumor, growth signals, cell death, radiotherapy
Protein & Peptide Letters
Title:Anticancer Peptides and Proteins: A Panoramic View
Volume: 20 Issue: 4
Author(s): M. S. Liberio, G. A. Joanitti, W. Fontes and M. S. Castro
Affiliation:
Keywords: Anticancer peptides, anticancer proteins, antimicrobial peptides, cancer, therapy, hemotherapeutics, tumor, growth signals, cell death, radiotherapy
Abstract: Despite progress in understanding carcinogenesis, cancer is still a major cause of morbidity and mortality worldwide. Treatment is complicated by the resistance to chemotherapeutics acquired by tumors, ability to repair damaged DNA, alteration of the interaction between drug and its target, and defects in the machinery that leads to apoptosis. The development of novel therapies based on biologically active peptides, especially antimicrobial peptides (AMPs), and proteins has emerged as a new strategy to defeat cancer.
Export Options
About this article
Cite this article as:
S. Liberio M., A. Joanitti G., Fontes W. and S. Castro M., Anticancer Peptides and Proteins: A Panoramic View, Protein & Peptide Letters 2013; 20 (4) . https://dx.doi.org/10.2174/0929866511320040002
DOI https://dx.doi.org/10.2174/0929866511320040002 |
Print ISSN 0929-8665 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5305 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Effects of Extracellular Matrix and Integrin Interactions on Airway Smooth Muscle Phenotype and Function: It Takes Two to Tango!
Current Respiratory Medicine Reviews Withdrawal Notice: The Recent Advancement in the Field of Super Paramagnetic Iron Oxide Nanoparticles (SPIONs) for Aiming Breast Cancer
Current Drug Metabolism Recent Advances in Oncogenic Roles of the TRPM7 Chanzyme
Current Medicinal Chemistry Tumour Cytochrome P450 and Drug Activation
Current Pharmaceutical Design The Epidemiological, Mechanistic and Potential Clinical Role of Androgen Receptor (AR) in Urothelial Carcinoma
Current Drug Targets GLP-1RA and SGLT2i: Cardiovascular Impact on Diabetic Patients
Current Hypertension Reviews Psychiatric Side Effects of Interferon Treatment
Current Drug Safety Antitumor Titanium Compounds
Mini-Reviews in Medicinal Chemistry Tea (Camellia sinensis (L.)): A Putative Anticancer Agent in Bladder Carcinoma?
Anti-Cancer Agents in Medicinal Chemistry Zebrafish Model in Drug Safety Assessment
Current Pharmaceutical Design Roles of SM22α in Cellular Plasticity and Vascular Diseases
Cardiovascular & Hematological Disorders-Drug Targets Disruption of the Keap1-Containing Ubiquitination Complex as an Antioxidant Therapy
Current Topics in Medicinal Chemistry Mechanisms of Drug Resistance to Vascular Endothelial Growth Factor (VEGF) Inhibitors
Anti-Cancer Agents in Medicinal Chemistry Patent Selections:
Recent Patents on Food, Nutrition & Agriculture The Chemical Defensive System in the Pathobiology of Idiopathic Environment- Associated Diseases
Current Drug Metabolism Subject Index to Volume 5
Current Drug Targets Positron Emission Tomography and Computer Tomography (PET/CT) in Prostate, Bladder, and Testicular Cancers
Current Medicinal Chemistry Anti-Angiogenic Peptides for Cancer Therapeutics
Current Pharmaceutical Biotechnology Post-Translational Modifications of PTEN and their Potential Therapeutic Implications
Current Cancer Drug Targets HCN Channels Modulators: The Need for Selectivity
Current Topics in Medicinal Chemistry