One-Pot, Three-Component Synthesis of Spirooxindoles Catalyzed by ZnO Nano-Rods in Solvent-Free Conditions

Mona      Hosseini-Sarvari; Mina      Tavakolian

doi:10.2174/138620712803901144

Abstract

Recyclable ZnO nano-rods catalyst as a most efficient and straightforward protocol for one-pot, threecomponent synthesis of spirooxindole derivatives at room temperature under solvent-free conditions in both reaction media and work-up procedure is described. This method is of great value because of its environmentally benign character, easy handling, high yields, convenient operation (grinding), room temperature, low cost and green.

Keywords: Multi-component reactions, nano rod ZnO, solvent-free, spirooxindoles.

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Combinatorial Chemistry & High Throughput Screening

Title:One-Pot, Three-Component Synthesis of Spirooxindoles Catalyzed by ZnO Nano-Rods in Solvent-Free Conditions

Volume: 15 Issue: 10

Author(s): Mona Hosseini-Sarvari and Mina Tavakolian

Affiliation:

Keywords: Multi-component reactions, nano rod ZnO, solvent-free, spirooxindoles.

Abstract: Recyclable ZnO nano-rods catalyst as a most efficient and straightforward protocol for one-pot, threecomponent synthesis of spirooxindole derivatives at room temperature under solvent-free conditions in both reaction media and work-up procedure is described. This method is of great value because of its environmentally benign character, easy handling, high yields, convenient operation (grinding), room temperature, low cost and green.

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Hosseini-Sarvari Mona and Tavakolian Mina, One-Pot, Three-Component Synthesis of Spirooxindoles Catalyzed by ZnO Nano-Rods in Solvent-Free Conditions, Combinatorial Chemistry & High Throughput Screening 2012; 15 (10) . https://dx.doi.org/10.2174/138620712803901144