Targeted Radiotherapy for Malignant Gliomas

Title:Targeted Radiotherapy for Malignant Gliomas

Volume: 9 Issue: 4

Author(s): Daniel S. Oh, David C. Adamson and John P. Kirkpatrick

Affiliation:

Keywords: Brachytherapy, charged particle therapy, glioma, radiotherapy, radiosurgery, radioimmunotherapy, biochemotherapies, Glioblastoma multiforme (GBM), radiosensitizers, CT scans

Abstract: Malignant glioma remains a disease with poor prognosis despite recent advances in the multidisciplinary care of this disease. Herein we review the evolution of and recent advances in radiation therapy for malignant glioma that have allowed for more targeted therapy, potentially improving efficacy while decreasing normal tissue toxicity. Current and emerging techniques are presented, including stereotactic radiotherapy and radiosurgery, brachytherapy, radioimmunotherapy, and charged particle therapy, as well as the combination of these modalities with novel targeted biochemotherapies.

Cite this article as:

S. Oh Daniel, C. Adamson David and P. Kirkpatrick John, Targeted Radiotherapy for Malignant Gliomas, Current Drug Discovery Technologies 2012; 9 (4) . https://dx.doi.org/10.2174/157016312803305870