Subtype-Selective Dopamine Receptor Radioligands for PET Imaging: Current Status and Recent Developments

Title:Subtype-Selective Dopamine Receptor Radioligands for PET Imaging: Current Status and Recent Developments

Volume: 19 Issue: 23

Author(s): A. Banerjee and O. Prante

Affiliation:

Keywords: Dopamine, D2, D3, D4, dopamine receptor, selectivity, subtype-selectivity, positron emission tomography, PET, radioligand, PET ligand, radiopharmaceutical, F-18, C-11

Abstract: This review presents a general overview of the subtype-selective dopamine receptor radioligands for in vivo imaging of dopamine receptor expression by positron emission tomography (PET). Besides the 11C- and 18F-labeled radioligands which are already in clinical use, a summary of subtype-selective radioligands which had been studied in vitro and in vivo is provided, which shines light onto the current status and recent developments in this field of radiopharmaceutical research.

Cite this article as:

Banerjee A. and Prante O., Subtype-Selective Dopamine Receptor Radioligands for PET Imaging: Current Status and Recent Developments, Current Medicinal Chemistry 2012; 19 (23) . https://dx.doi.org/10.2174/092986712802002518