Abstract
There has long been a concern that all psychotropics may have adverse cardiac effects including prolongation of the QT interval. The recent expanded use of the atypical antipsychotics has increased these concerns. This is a selective review of the effect of the major classes of psychotropic drugs on the QT interval. The review also includes a review of methadone given the high co-morbidity between major psychiatric disorders and substance use disorders.
Keywords: Acquired LQTS, drug-induced QT syndrome, methadone, psychiatry, psychotropics, QT interval, QT prolongation, sudden cardiac death, cardiometabolic risk, arrhythmogenic, mesoridazine, phenothiazines, hypomagnesemia, epidemiologic, tachyarrhythmias
Current Psychopharmacology
Title: Psychotropics and Methadone in Acquired Long QT Syndrome
Volume: 1
Author(s): Stephan Carlson and Russell Joffe
Affiliation:
Keywords: Acquired LQTS, drug-induced QT syndrome, methadone, psychiatry, psychotropics, QT interval, QT prolongation, sudden cardiac death, cardiometabolic risk, arrhythmogenic, mesoridazine, phenothiazines, hypomagnesemia, epidemiologic, tachyarrhythmias
Abstract: There has long been a concern that all psychotropics may have adverse cardiac effects including prolongation of the QT interval. The recent expanded use of the atypical antipsychotics has increased these concerns. This is a selective review of the effect of the major classes of psychotropic drugs on the QT interval. The review also includes a review of methadone given the high co-morbidity between major psychiatric disorders and substance use disorders.
Export Options
About this article
Cite this article as:
Carlson Stephan and Joffe Russell, Psychotropics and Methadone in Acquired Long QT Syndrome, Current Psychopharmacology 2012; 1 (2) . https://dx.doi.org/10.2174/2211556011201020183
DOI https://dx.doi.org/10.2174/2211556011201020183 |
Print ISSN 2211-5560 |
Publisher Name Bentham Science Publisher |
Online ISSN 2211-5579 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Immunologic Modulations to Enhance Post-Stroke Recovery
Current Immunology Reviews (Discontinued) Clinical Characteristics and Treatment of Cardiomyopathies in Children
Current Cardiology Reviews Tofacitinib, an Oral Janus Kinase Inhibitor: Perspectives in Dermatology
Current Medicinal Chemistry Tissue Distribution and Pharmacodynamics: A Complicated Relationship
Current Drug Metabolism A1 Adenosine Receptor Agonists: Medicinal Chemistry and Therapeutic Potential
Current Pharmaceutical Design Malnutrition in Patients with End-Stage Renal Disease - Anorexia,Cachexia and Catabolism
Current Nutrition & Food Science Nutritional Antioxidants Mechanisms of Action, Analyses of Activities and Medical Applications
Current Medicinal Chemistry - Immunology, Endocrine & Metabolic Agents Duration of Dual Antiplatelet Therapy After Coronary Stenting
Current Pharmaceutical Design Impact of CYP2D6 Genetic Variation on the Response of the Cardiovascular Patient to Carvedilol and Metoprolol
Current Drug Metabolism Pharmacological and Biological Activities of Xanthones
Anti-Infective Agents in Medicinal Chemistry Metabolic Effects of Bile Acids in the Gut in Health and Disease
Current Medicinal Chemistry An Overview of Innovations in Analysis and Beneficial Health Effects of Wine Polyphenols
Mini-Reviews in Medicinal Chemistry Vascular Endothelial Function Change in Elderly Chinese Patients with Obstructive Sleep Apnea and its Association with Coronary Heart Disease
Vascular Disease Prevention (Discontinued) Clinical Management of Arrhythmogenic Right Ventricular Cardiomyopathy: An Update
Current Pharmaceutical Design Drug-Induced Hypokalaemia
Current Drug Safety Perioperative Considerations in Diabetic Patients
Current Diabetes Reviews Leptin-Induced Endothelial Dysfunction: A Target for Therapeutic Interventions
Current Pharmaceutical Design Drugs Polypharmacology by In Silico Methods: New Opportunities in Drug Discovery
Current Pharmaceutical Design The Role of Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) in Cardiovascular Homeostasis: A Non-Systematic Literature Review
Current Cardiology Reviews CPR Education
Current Pediatric Reviews