Chemistry and Biology of Iminosugar Di- and Oligosaccharides

Title: Chemistry and Biology of Iminosugar Di- and Oligosaccharides

Volume: 3 Issue: 3

Author(s): Pedro Merino, Ignacio Delso, Eduardo Marca, Tomas Tejero and Rosa Matute

Affiliation:

Keywords: Iminosugars, oligosaccharides, glycosidase inhibitors, azasugars, piperidines

Abstract: This review will describe the recent advances in the field of oligosaccharides containing at least one unit of a polyhydroxylated piperidine or pyrrolidine. The review will cover both chemical and biological aspects concerning their preparation and/or occurrence in Nature as well as their biological properties which include glycosylase, and glycosyl transferase inhibition, among others. These enzymatic inhibitory properties are the basis for the potential use of the title compounds in viral infections, cancer and genetic disorders.

Cite this article as:

Merino Pedro, Delso Ignacio, Marca Eduardo, Tejero Tomas and Matute Rosa, Chemistry and Biology of Iminosugar Di- and Oligosaccharides, Current Chemical Biology 2009; 3 (3) . https://dx.doi.org/10.2174/2212796810903030253