Abstract
A novel class of chiral ammonium and imidazolium-based ionic liquids containing a chiral moiety and a free hydroxyl function has been designed and synthesized using (-)-ephedrine, isosorbide and isosmannide as naturally chiral sources. Some physical properties of these salts such as melting point, glass-transition temperature, thermal degradation, chemical stability and specific rotation have been characterized. These chiral ionic liquids were found to catalyze the asymmetric Baylis-Hillman reaction, aza Diels-Alder reaction and Michael addition giving good yields and moderate stereoselectivities. Chiral ionic liquids are recycled while their efficiency is preserved.
Keywords: Asymmetric aza Diels-Alder reaction, Asymmetric Baylis-Hillman reaction, Ephedrine, Chiral ionic liquids, Isomannide, isosorbide, Michael addition, Microwave-activation, conventional organic solvents, incombustibility, racemates
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