Design, Synthesis of Novel Quinazolone Alkaloids Derivatives as Potential Antitumor Agents

Title: Design, Synthesis of Novel Quinazolone Alkaloids Derivatives as Potential Antitumor Agents

Volume: 7 Issue: 4

Author(s): Youguang Zheng, Min Sun, Yi Liu, Mingdong Li and Min Ji

Affiliation:

Keywords: Quinazolone alkaloids, human pancreatic cancer, Miacapa2, EGFR, X-ray crystal structure, prostate cancer, EA, MS, IR, 13CNMR, 1HNMR

Abstract: Several novel quinazolone alkaloids derivatives were synthesized. Some of the target compounds were determined against human prostate cancer DU145 and pancreatic cancer Miacapa2 cells in vitro. The entire compounds had been identified by 1HNMR, 13CNMR, IR, MS and EA.

Cite this article as:

Zheng Youguang, Sun Min, Liu Yi, Li Mingdong and Ji Min, Design, Synthesis of Novel Quinazolone Alkaloids Derivatives as Potential Antitumor Agents, Medicinal Chemistry 2011; 7 (4) . https://dx.doi.org/10.2174/157340611796150987