Abstract
New Platinum and Ruthenium complexes display antitumour and antimetastatic potentials and lower host toxicities. This mini-review examines some the more recent developments in this field, and explores their interactions with biologically-relevant species. The article also refers to more recent work in the area of molybdenum and copper(II) chemistry.
Keywords: Cisplatin, BBR3464, picoplatin, satraplatin, lipoplatin, NAMI-A, KP1019, RAPTA, cancer, chemotherapeutics
Mini-Reviews in Medicinal Chemistry
Title: New Platinum and Ruthenium Complexes - the Latest Class of Potential Chemotherapeutic Drugs - a Review of Recent Developments in the Field
Volume: 9 Issue: 13
Author(s): Amr Amin and Michael A. Buratovich
Affiliation:
Keywords: Cisplatin, BBR3464, picoplatin, satraplatin, lipoplatin, NAMI-A, KP1019, RAPTA, cancer, chemotherapeutics
Abstract: New Platinum and Ruthenium complexes display antitumour and antimetastatic potentials and lower host toxicities. This mini-review examines some the more recent developments in this field, and explores their interactions with biologically-relevant species. The article also refers to more recent work in the area of molybdenum and copper(II) chemistry.
Export Options
About this article
Cite this article as:
Amin Amr and Buratovich A. Michael, New Platinum and Ruthenium Complexes - the Latest Class of Potential Chemotherapeutic Drugs - a Review of Recent Developments in the Field, Mini-Reviews in Medicinal Chemistry 2009; 9 (13) . https://dx.doi.org/10.2174/138955709790361566
DOI https://dx.doi.org/10.2174/138955709790361566 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Mechanisms Underlying Beneficial Health Effects of Tea Catechins to Improve Insulin Resistance and Endothelial Dysfunction
Endocrine, Metabolic & Immune Disorders - Drug Targets A Method for Analyzing Two-locus Epistasis of Complex Diseases based on Decision Tree and Mutual Entropy
Current Proteomics New Indications for Established Drugs: Combined Tumor-Stroma-Targeted Cancer Therapy with PPARγ Agonists, COX-2 Inhibitors, mTOR Antagonists and Metronomic Chemotherapy
Current Cancer Drug Targets Fyn Kinase in Brain Diseases and Cancer: The Search for Inhibitors
Current Medicinal Chemistry Neurotrophic Factors in Combination: A Possible new Therapeutic Strategy to Influence Pathophysiology of Spinal Cord Injury and Repair Mechanisms
Current Pharmaceutical Design Optimizing Gene Silencing Strategies for Pancreatic Cancer
Current Cancer Therapy Reviews Hyperthermia Associated Osteonecrosis in Young Patients with Pelvic Malignancies
Anti-Cancer Agents in Medicinal Chemistry Nanotechnology in Therapeutics – Current Technologies and Applications
Current Nanoscience Quinone-Based Drugs: An Important Class of Molecules in Medicinal Chemistry
Medicinal Chemistry Identification of KEY lncRNAs and mRNAs Associated with Oral Squamous Cell Carcinoma Progression
Current Bioinformatics Epigenetic Changes Induced by Green Tea Catechins a re Associated with Prostate Cancer
Current Molecular Medicine Circumventing Immune Tolerance Through Epigenetic Modification
Current Pharmaceutical Design Nano-engineered Adsorbent for the Removal of Dyes from Water: A Review
Current Analytical Chemistry Probiotics: From Functional Foods to Pharmaceutical Products
Current Pharmaceutical Biotechnology A Mini Review on the Chemistry and Neuroprotective Effects of Silymarin
Current Drug Targets Dicoumarol: A Drug which Hits at Least Two Very Different Targets in Vitamin K Metabolism
Current Drug Targets Enhanced Floating and Intragastric Release of 5-Flourouracil through Sesame Oil Entrapped Gellan Composite Hydrogel Beads
Current Drug Therapy Exploring Pharmacological Significance of Chalcone Scaffold: A Review
Current Medicinal Chemistry Modulation of Tumour-Related Signaling Pathways by Natural Pentacyclic Triterpenoids and their Semisynthetic Derivatives
Current Medicinal Chemistry Hypoxia: Targeting the Tumour
Anti-Cancer Agents in Medicinal Chemistry