Protein NMR-Based Screening in Drug Discovery

E.   R.   Zartler; M.   J.   Shapiro

doi:10.2174/138161206778743619

Abstract

Protein NMR as a screening tool in drug discovery has become prominent within the past ten years. Advances in protein manipulation, whether by biological means (labeling) or physical means (NMR), have created a powerful method that is able to observe ligand-target interactions in solution.

Keywords: NMR, Protein labeling, Chemical Shift Perturbtation, RAMPED-UP

« Previous Next »