Non-Globular Structures of Tandem Repeats in Proteins

Title: Non-Globular Structures of Tandem Repeats in Proteins

Volume: 16 Issue: 11

Author(s): Norio Matsushima, Takanori Tanaka and Robert H. Kretsinger

Affiliation:

Keywords: Tandem repeats, intrinsically unstructured protein, structural change, ligand interaction, rapid evolution, concerted evolution

Abstract: There are two classes of tandem repeats in proteins - globular and non-globular. There are two subclasses of non-globular repeats. The first, such as collagen, form stable helices. Members of the second are flexible and somewhat disordered both in vitro and in vivo. This review focuses on this second subclass.

Cite this article as:

Matsushima Norio, Tanaka Takanori and Kretsinger H. Robert, Non-Globular Structures of Tandem Repeats in Proteins, Protein & Peptide Letters 2009; 16 (11) . https://dx.doi.org/10.2174/092986609789353745