Electrochemical Biosensors for Superoxide Anion

Title: Electrochemical Biosensors for Superoxide Anion

Volume: 2 Issue: 1

Author(s): Yang Tian, Lanqun Mao and Takeo Ohsaka

Affiliation:

Keywords: Superoxide anion (O2), Electrochemical biosensors, Superoxide dismutase (SOD), Cytochrome c, Self-assembled monolayer (SAM), in vivo

Abstract: The determination of superoxide anion (O2 .-) is of great physiological and pathological importance since O2 .- is considered to be involved in the etiology of aging, cancer, and progressive neurodegenerative diseases such as Parkinsons disease. The determination of the local concentration of O2 .- has been a relatively challenging analytical problem because of the low concentration, high reactivity and short lifetime of O2 .- in biological systems. This review raises a number of methods, highlighting electrochemical methodologies, for the determination of O2 .-. These electrochemical sensors and biosensors and their analytical characteristics are discussed in detail.

Cite this article as:

Tian Yang, Mao Lanqun and Ohsaka Takeo, Electrochemical Biosensors for Superoxide Anion, Current Analytical Chemistry 2006; 2 (1) . https://dx.doi.org/10.2174/157341106775197376