Abstract
Paeonol, a naturally existing compound found in Chinese traditional medicinal herb Cortex Moutan, the root bark of Paeonia suffruticosa Andr., has shown anticancer, antiinflammatory and anti-cardiovascular disease activities. These biological activities largely rely on the mechanisms underlying. It has been shown that these biological activities of paeonol are largely related to the inflammatory NF-κB cell signaling pathways. In this minireview, we are the first to summarize biological activities and associated pathways of paeonol.
Keywords: Antitumor, anti-inflammatory, anticancer, in vivo, in vitro, paeonol.
Graphical Abstract
Current Traditional Medicine
Title:Paeonol, a Powerful Natural Product with Broad Biological Spectra by Inhibiting Inflammatory Pathway
Volume: 2 Issue: 2
Author(s): Bixi Tang, Cai-Yun Peng, Kwame Oteng Darko, Ting Tao, Yanjun Huang, Qiongli Su and Xiaoping Yang
Affiliation:
Keywords: Antitumor, anti-inflammatory, anticancer, in vivo, in vitro, paeonol.
Abstract: Paeonol, a naturally existing compound found in Chinese traditional medicinal herb Cortex Moutan, the root bark of Paeonia suffruticosa Andr., has shown anticancer, antiinflammatory and anti-cardiovascular disease activities. These biological activities largely rely on the mechanisms underlying. It has been shown that these biological activities of paeonol are largely related to the inflammatory NF-κB cell signaling pathways. In this minireview, we are the first to summarize biological activities and associated pathways of paeonol.
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Cite this article as:
Tang Bixi, Peng Cai-Yun, Darko Oteng Kwame, Tao Ting, Huang Yanjun, Su Qiongli and Yang Xiaoping, Paeonol, a Powerful Natural Product with Broad Biological Spectra by Inhibiting Inflammatory Pathway, Current Traditional Medicine 2016; 2 (2) . https://dx.doi.org/10.2174/2215083802666161025162252
DOI https://dx.doi.org/10.2174/2215083802666161025162252 |
Print ISSN 2215-0838 |
Publisher Name Bentham Science Publisher |
Online ISSN 2215-0846 |
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