SELDI Protein Chip Technology for the Detection of Serum Biomarkers for Liver Disease

Title: SELDI Protein Chip Technology for the Detection of Serum Biomarkers for Liver Disease

Volume: 16 Issue: 5

Author(s): Lei Chen, Sarwat Fatima, Jirun Peng and Xisheng Leng

Affiliation:

Keywords: Surface enhanced laser desorption/ionization, proteomics, biomarker, liver diseases

Abstract: The need to identify disease biomarkers is critical to ensure fast diagnosis and timely treatment. Surface enhanced laser desorption/ionization time-of-fight mass spectrometry (SELDI-TOF-MS) is a widely used technology platform for diagnostic biomarker discovery. This short review provides an overview of how it functions and also describes its advantages and drawbacks.

Cite this article as:

Chen Lei, Fatima Sarwat, Peng Jirun and Leng Xisheng, SELDI Protein Chip Technology for the Detection of Serum Biomarkers for Liver Disease, Protein & Peptide Letters 2009; 16 (5) . https://dx.doi.org/10.2174/092986609788167851