Cannabinoid System in Neurodegeneration: New Perspectives in Alzheimers Disease

Title: Cannabinoid System in Neurodegeneration: New Perspectives in Alzheimers Disease

Volume: 9 Issue: 5

Author(s): N. E. Campillo and J. A. Paez

Affiliation:

Keywords: Cannabinoid, endocannabinoid, cannabinoid receptors, alzheimer's disease, dementia, CB2 agonist

Abstract: Alzheimers disease is a chronic and progressive neurodegenerative disorder. The presence of functional cannabinoid CB2 receptors in central nervous system (CNS) has provoked that this receptor and its agonist ligands are now considered as promising pharmacological targets for neurological diseases. Herein, we review the evidences supporting the potential role of the ECS as a therapeutic target, focused on CB2 receptor and its ligands, for the treatment of Alzheimer s disease.

Cite this article as:

Campillo E. N. and Paez A. J., Cannabinoid System in Neurodegeneration: New Perspectives in Alzheimers Disease, Mini-Reviews in Medicinal Chemistry 2009; 9 (5) . https://dx.doi.org/10.2174/138955709788167628