Novel Detection System for Plant Protein Production of Pharmaceuticals and Impact on Conformational Diseases

Title: Novel Detection System for Plant Protein Production of Pharmaceuticals and Impact on Conformational Diseases

Volume: 17 Issue: 6

Author(s): Kerstin A. Nagel, Bernd Kastenholz, Frank Gilmer, Ulrich Schurr and Achim Walter

Affiliation:

Keywords: Protein folding, Alzheimer's disease, molecular farming, PMPs, value-added biochemicals, methodologial strategy

Abstract: State-of-the-art biochemistry methods in combination with an automated phenotyping method demonstrate the high potential of transgenic tobacco plants in producing properly-folded therapeutic proteins for the treatment of protein-misfolding diseases (e.g., Alzheimers disease). This molecular farming approach led to highest protein production of hydroponically- grown tobacco compared to other growth substrates generally used in plant cultivation.

Cite this article as:

A. Nagel Kerstin, Kastenholz Bernd, Gilmer Frank, Schurr Ulrich and Walter Achim, Novel Detection System for Plant Protein Production of Pharmaceuticals and Impact on Conformational Diseases, Protein & Peptide Letters 2010; 17 (6) . https://dx.doi.org/10.2174/092986610791190282