Molecular Cloning and Expression of Several New Anopheles cracens Epsilon Class Glutathione Transferases

Title: Molecular Cloning and Expression of Several New Anopheles cracens Epsilon Class Glutathione Transferases

Volume: 16 Issue: 1

Author(s): Jeerang Wongtraku, Jantana Wongsantichon, Ardcharaporn Vararattanavech, Posri Leelapat, La-aied Prapanthadara and Albert J. Ketterman

Affiliation:

Keywords: Glutathione transferase, An. cracens, Epsilon class, 4-HNE, lipid peroxidation, oxidative stress

Abstract: Glutathione transferases, GSTs, are detoxification proteins that are found in most organisms. The acGSTE3-3 had the ability to conjugate 4-hydroxynonenal, a cytotoxic lipid peroxidation product. Although other Epsilon GSTs showed roles in insecticide metabolism, the acGSTE3-3 appeared to have a major role in detoxifying lipid peroxidation products conferring protection against oxidative damage.

Cite this article as:

Wongtraku Jeerang, Wongsantichon Jantana, Vararattanavech Ardcharaporn, Leelapat Posri, Prapanthadara La-aied and Ketterman J. Albert, Molecular Cloning and Expression of Several New Anopheles cracens Epsilon Class Glutathione Transferases, Protein & Peptide Letters 2009; 16 (1) . https://dx.doi.org/10.2174/092986609787049367