Synthesis of Marine Natural Products with Antimalarial Activity

Title: Synthesis of Marine Natural Products with Antimalarial Activity

Volume: 8 Issue: 12

Author(s): Ines Mancini, Graziano Guella and Andrea Defant

Affiliation:

Keywords: Natural products, marine metabolites, drug discovery, synthesis, retrosynthetic analysis, antiprotozoal, antimalarial, antiplasmodial

Abstract: The role played by synthetic organic chemistry of marine metabolites as potential leads for drug discovery of antimalarial agents is discussed. Syntheses of the most promising molecules are summarized, with emphasis on structureactivity relationship (SAR) studies and their mechanism of action.

Cite this article as:

Mancini Ines, Guella Graziano and Defant Andrea, Synthesis of Marine Natural Products with Antimalarial Activity, Mini-Reviews in Medicinal Chemistry 2008; 8 (12) . https://dx.doi.org/10.2174/138955708786141007