Abstract
The reaction of indole with acetone in the presence of mineral/Lewis acid continues to be a fascinating area for investigation since 1913, specially due to the instability of the indolyl carbinol being generated in situ. We report here the synthesis of a novel spiro heterocyclic system obtained during the study of this reaction using BF3.Et2O.
Keywords: Indole, acetone, spiro system, X-ray crystallography
Letters in Organic Chemistry
Title: Electrophilic Substitution Reaction of Indole: Part XXII-Synthesis of a Novel Spiro Heterocyclic System
Volume: 5 Issue: 5
Author(s): Anupam Nayak, Asima Chatterjee, Julie Banerji, Munmun Saha, Sukumar Manna, Sanchayita Kanrar and Tomoyasu Hirose
Affiliation:
Keywords: Indole, acetone, spiro system, X-ray crystallography
Abstract: The reaction of indole with acetone in the presence of mineral/Lewis acid continues to be a fascinating area for investigation since 1913, specially due to the instability of the indolyl carbinol being generated in situ. We report here the synthesis of a novel spiro heterocyclic system obtained during the study of this reaction using BF3.Et2O.
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Cite this article as:
Nayak Anupam, Chatterjee Asima, Banerji Julie, Saha Munmun, Manna Sukumar, Kanrar Sanchayita and Hirose Tomoyasu, Electrophilic Substitution Reaction of Indole: Part XXII-Synthesis of a Novel Spiro Heterocyclic System, Letters in Organic Chemistry 2008; 5 (5) . https://dx.doi.org/10.2174/157017808784872070
DOI https://dx.doi.org/10.2174/157017808784872070 |
Print ISSN 1570-1786 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6255 |
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