Abstract
Antibiotic resistance nowadays plays an important role in the treatment of uncomplicated and complicated urinary tract infections (UTIs). In uncomplicated UTI efforts are made to use antibiotic substances exclusively for this indication. In complicated UTI substances with activity against bacteria harbouring common resistance mechanisms are investigated. Additionally pharmacokinetic/ pharmacodynamic parameters are used to improve dosing strategies.
Keywords: Urinary tract infections, uncomplicated UTI, complicated UTI, antibiotic resistance, pharmacokinetics, pharmacodynamics
Mini-Reviews in Medicinal Chemistry
Title: Current Anti-Infective Treatment of Bacterial Urinary Tract Infections
Volume: 8 Issue: 8
Author(s): Florian M.E. Wagenlehner, Christine Wagenlehner, Kurt G. Naber and W. Weidner
Affiliation:
Keywords: Urinary tract infections, uncomplicated UTI, complicated UTI, antibiotic resistance, pharmacokinetics, pharmacodynamics
Abstract: Antibiotic resistance nowadays plays an important role in the treatment of uncomplicated and complicated urinary tract infections (UTIs). In uncomplicated UTI efforts are made to use antibiotic substances exclusively for this indication. In complicated UTI substances with activity against bacteria harbouring common resistance mechanisms are investigated. Additionally pharmacokinetic/ pharmacodynamic parameters are used to improve dosing strategies.
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Cite this article as:
Wagenlehner M.E. Florian, Wagenlehner Christine, Naber G. Kurt and Weidner W., Current Anti-Infective Treatment of Bacterial Urinary Tract Infections, Mini-Reviews in Medicinal Chemistry 2008; 8 (8) . https://dx.doi.org/10.2174/138955708784912210
DOI https://dx.doi.org/10.2174/138955708784912210 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
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