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Mini-Reviews in Medicinal Chemistry

Editor-in-Chief

ISSN (Print): 1389-5575
ISSN (Online): 1875-5607

Natural Marine Anti-inflammatory Products

Author(s): Maria Jose Abad, Luis Miguel Bedoya and Paulina Bermejo

Volume 8, Issue 8, 2008

Page: [740 - 754] Pages: 15

DOI: 10.2174/138955708784912148

Price: $65

Abstract

The marine environment has been shown to be the source of a great diversity of chemical structures with promising biological activities. The isolation, biological evaluation, chemical properties and synthetic elaborations of the products of marine organisms and microorganisms have attracted the attention of organic chemists, medicinal chemists, biologists and pharmacists. Marine organisms and microorganisms have provided a large proportion of the natural antiinflammatory products over the last years. Marine organisms include green algae, brown algae, red algae, sponges, coelenterates, bryozoans, molluscs, tunicates, echinoderms, miscellaneous marine organisms and marine microorganisms and phytoplankton. This review describes current progress in the development of a selection of new anti-inflammatory agents from marine sources. The chemistry and biological evaluation are discussed.

Keywords: Spirulina, Anti-inflammatory, terpenoids, COX pathway, Alkaloids

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