Discovery-Based Strategies for Studying Platelet Function

Title: Discovery-Based Strategies for Studying Platelet Function

Volume: 8 Issue: 4

Author(s): R. Flaumenhaft and J. R. Dilks

Affiliation:

Keywords: Platelets, chemical genetics, bioinformatics

Abstract: The platelet is an anucleate cell, complicating efforts to study platelet function by traditional genetic means. Discovery-based strategies have lead to the identification of pharmacological agents capable of targeting specific proteins critical for platelet activation. This review will address the evolution of discovery-based strategies to identify probes that are at once useful reagents for studying platelet activation and effective therapeutics.

Cite this article as:

Flaumenhaft R. and Dilks R. J., Discovery-Based Strategies for Studying Platelet Function, Mini-Reviews in Medicinal Chemistry 2008; 8 (4) . https://dx.doi.org/10.2174/138955708783955971