Abstract
The synthesis of a novel series of isatin derivatives bearing an acetamide group is described. These 2-(2,3- dioxo-indolin-1-yl)acetamide derivatives were synthesized by N-carboxymethylation of isatin followed by conversion of the carboxylic acid function into a tertiary amide. In a preliminary study, this series of compounds were tested in vitro for their biological activity, against various strains of bacteria.
Keywords: Isatin, acetamide, tertiary amide, in vitro biological activity
Related Books
2-Deoxy-D-Glucose: Chemistry and Biology
Chiral Ionic Liquids: Applications in Chemistry and Technology
Basics of Organic Chemistry: A Textbook for Undergraduate Students
Advances in Organic Synthesis
The Synthetic Methods, Structures, and Properties of the Ca-C σ Bond Organocalcium Containing Compounds
Advances in Organic Synthesis
Chemistry of Bipyrazoles: Synthesis and Applications
Advances in Organic Synthesis
Advanced Nanocatalysis for Organic Synthesis and Electroanalysis
Advances in Organic Synthesis
20