Fullerenes in Medicinal Chemistry and their Biological Applications

Title: Fullerenes in Medicinal Chemistry and their Biological Applications

Volume: 1 Issue: 4

Author(s): N. Tagmatarchis and H. Shinohara

Affiliation:

Keywords: Fullerenes, UV-Visible absorption, Photodynamic Therapy, Enzymatic Inhibition, Cell signaling, Apoptosis, Neuroprotective antioxidants, Endohedral Metallofullerenes, MRI contrast agents

Abstract: The isolation and preparation ten years ago of the fullerenes in bulk quantities, sparked off a truly remarkable interdisciplinary research activity, encompassing diverse fields of chemistry, physics, materials science and medicinal chemistry. Pharmaceutical and biological studies have revealed that fullerene-based compounds exhibit various types of biological activity either in vitro or in vivo and are discussed in this review.

Cite this article as:

Tagmatarchis N. and Shinohara H., Fullerenes in Medicinal Chemistry and their Biological Applications, Mini-Reviews in Medicinal Chemistry 2001; 1 (4) . https://dx.doi.org/10.2174/1389557013406684