Phylogenetic and Functional Classification of ATP-Binding Cassette (ABC) Systems

Philippe      Bouige; David      Laurent; Linda      Piloyan; Elie      Dassa

doi:10.2174/1389203023380486

Abstract

ATP binding cassette (ABC) systems constitute one of the most abundant superfamilies of proteins. They are involved in the transport of a wide variety of substances, but also in many cellular processes and in their regulation. In this paper, we made a comparative analysis of the properties of ABC systems and we provide a phylogenetic and functional classification. This analysis will be helpful to accurately annotate ABC systems discovered during the sequencing of the genome of living organisms and to identify the partners of the ABC ATPases.

Keywords: Phylogenetic, ATP-Binding, DRI Family, BPD Transporters

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