Abstract
Neuropathic pain is still far from being adequately dealt with. Under this name, several clinical entities have been considered and most of them only share several painful ailments. At present, the available treatments can only alleviate the pain of roughly half of the patients, and their effectiveness is often limited by the appearance of the intolerable side effects. In this review, we will consider the pathophysiology of neuropathic pain to understand the basis of pharmacological treatments that are currently being investigated. Some examples of these drugs will also be considered.
Keywords: pain, neuropathic pain, analgesics, pathophysiology, allodynia, hyperalgesia, experimental models, new drugs
Mini-Reviews in Medicinal Chemistry
Title: Neuropathic Pain: Some Clues for Future Drug Treatments
Volume: 3 Issue: 7
Author(s): J. E. Banos, G. Sanchez, F. Berrendero and R. Maldonado
Affiliation:
Keywords: pain, neuropathic pain, analgesics, pathophysiology, allodynia, hyperalgesia, experimental models, new drugs
Abstract: Neuropathic pain is still far from being adequately dealt with. Under this name, several clinical entities have been considered and most of them only share several painful ailments. At present, the available treatments can only alleviate the pain of roughly half of the patients, and their effectiveness is often limited by the appearance of the intolerable side effects. In this review, we will consider the pathophysiology of neuropathic pain to understand the basis of pharmacological treatments that are currently being investigated. Some examples of these drugs will also be considered.
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Cite this article as:
Banos E. J., Sanchez G., Berrendero F. and Maldonado R., Neuropathic Pain: Some Clues for Future Drug Treatments, Mini-Reviews in Medicinal Chemistry 2003; 3 (7) . https://dx.doi.org/10.2174/1389557033487773
DOI https://dx.doi.org/10.2174/1389557033487773 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
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