Immunotoxins and Other Conjugates: Pre-clinical Studies

A.      Bolognesi; L.      Polito

doi:10.2174/1389557043403864

Abstract

A wide variety of conjugates containing RIPs, of either chemical or recombinant type, have been made and tested against dangerous cells in vitro and in animal models. Many of these pre-clinical studies will be reviewed here dividing them on the basis of the target cell and the surface molecule specifically recognized.

Keywords: ribosome-inactivating proteins, toxins, conjugates, immunotoxins, targeting, immunotherapy

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