Immunotoxins and Other Conjugates: Preparation and General Characteristics

Giulio      Fracasso; Giuseppe      Bellisola; Deborah      Castelletti; Giuseppe      Tridente; Marco      Colombatti

doi:10.2174/1389557043403909

Abstract

Targeted toxins represent an invaluable tool offering a wide range of potential applications, both in experimental models and in the clinics. Here we will review several aspects related to the preparation and properties of carrier molecule-toxin heteroconjugates and fusion toxins.

Keywords: toxins, ribosome inactivating proteins, immunotoxins, targeting

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Mini-Reviews in Medicinal Chemistry

Title: Immunotoxins and Other Conjugates: Preparation and General Characteristics

Volume: 4 Issue: 5

Author(s): Giulio Fracasso, Giuseppe Bellisola, Deborah Castelletti, Giuseppe Tridente and Marco Colombatti

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Keywords: toxins, ribosome inactivating proteins, immunotoxins, targeting

Abstract: Targeted toxins represent an invaluable tool offering a wide range of potential applications, both in experimental models and in the clinics. Here we will review several aspects related to the preparation and properties of carrier molecule-toxin heteroconjugates and fusion toxins.

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Fracasso Giulio, Bellisola Giuseppe, Castelletti Deborah, Tridente Giuseppe and Colombatti Marco, Immunotoxins and Other Conjugates: Preparation and General Characteristics, Mini-Reviews in Medicinal Chemistry 2004; 4 (5) . https://dx.doi.org/10.2174/1389557043403909