Synthesis of Pyranoid Sugar α-Amino Acid Derivatives from 2-Oxo-Dgluconic Acid

Title: Synthesis of Pyranoid Sugar α-Amino Acid Derivatives from 2-Oxo-Dgluconic Acid

Volume: 2 Issue: 2

Author(s): Stephan Schmidt, Lars Teich, Mohamed Khodja and Dieter Sicker

Affiliation:

Keywords: 2-oxo-D-gluconic acid, 2-oxo-D-gluconate, sugar amino acids, 2-amino-D-arabino-hex-2-ulopyranosonic acid

Abstract: Syntheses of novel sugar amino acid derivatives with the 2-amino-D-arabino-hex-2- ulopyranosonic acid skeleton are described, with the anomeric centre being the α-C-atom of the amino acid unit. The starting material for the syntheses reported is 2-oxo-D-gluconic acid which has been obtained by fermentation of D-glucose. Starting from this source differently protected pyranoid α-sugar amino acids as well as derivatives like dipeptides could be synthesized.

Cite this article as:

Schmidt Stephan, Teich Lars, Khodja Mohamed and Sicker Dieter, Synthesis of Pyranoid Sugar α-Amino Acid Derivatives from 2-Oxo-Dgluconic Acid, Letters in Organic Chemistry 2005; 2 (2) . https://dx.doi.org/10.2174/1570178053202946