Crystal Structure of Non-Fused Glutathione S-Transferase from Schistosoma 709 japonicum in Complex with Glutathione

I.      Kursula; A.   M.   Heape; P.      Kursula

doi:10.2174/0929866054696154

Abstract

Schistosoma japonicum glutathione S-transferase (SjGST) is a common fusion tag in recombinant protein production, and its 3-dimensional structure has been studied in the context of drug design. We have determined the crystal structure of non-fused SjGST complexed with glutathione, and compare it to complexes between glutathione and SjGST fusion proteins.

Keywords: glutathione, gst, crystal structure, fusion protein, schistosoma japonicum

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Protein & Peptide Letters

Title: Crystal Structure of Non-Fused Glutathione S-Transferase from Schistosoma 709 japonicum in Complex with Glutathione

Volume: 12 Issue: 7

Author(s): I. Kursula, A. M. Heape and P. Kursula

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Keywords: glutathione, gst, crystal structure, fusion protein, schistosoma japonicum

Abstract: Schistosoma japonicum glutathione S-transferase (SjGST) is a common fusion tag in recombinant protein production, and its 3-dimensional structure has been studied in the context of drug design. We have determined the crystal structure of non-fused SjGST complexed with glutathione, and compare it to complexes between glutathione and SjGST fusion proteins.

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Kursula I., Heape M. A. and Kursula P., Crystal Structure of Non-Fused Glutathione S-Transferase from Schistosoma 709 japonicum in Complex with Glutathione, Protein & Peptide Letters 2005; 12 (7) . https://dx.doi.org/10.2174/0929866054696154