Recent Developments in the Understanding of Nuclear Protein Import

S.M. Liu; W.M. Liu

doi:10.2174/092986607781483895

Abstract

The process of nucleocytoplasmic exchange of various macromolecules and metabolites between the nuclear and cytoplasmic compartment is crucial for cell function and survival. It is also closely involved with several pathogeneses including cancer and viral infections. Here, we will discuss the current understanding of the classical nuclear import pathway and the factors that are essential for this process.

Keywords: Nuclear transport, ran switch, importin, influenza

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Protein & Peptide Letters

Title: Recent Developments in the Understanding of Nuclear Protein Import

Volume: 14 Issue: 7

Author(s): S.M. Liu and W.M. Liu

Affiliation:

Keywords: Nuclear transport, ran switch, importin, influenza

Abstract: The process of nucleocytoplasmic exchange of various macromolecules and metabolites between the nuclear and cytoplasmic compartment is crucial for cell function and survival. It is also closely involved with several pathogeneses including cancer and viral infections. Here, we will discuss the current understanding of the classical nuclear import pathway and the factors that are essential for this process.

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S.M. Liu and W.M. Liu , Recent Developments in the Understanding of Nuclear Protein Import, Protein & Peptide Letters 2007; 14 (7) . https://dx.doi.org/10.2174/092986607781483895