Suzuki-Miyaura Cross-Coupling Reaction in the Functionalization of the C Ring of Morphinans

Attila      Sipos; Sandor      Berenyi

doi:10.2174/157017807780414145

Abstract

New methods have been developed for the functionalization of the non-aromatic C ring of morphinans with Suzuki-Miyaura cross-coupling of sulfonates and bromides.

Keywords: Suzuki-Miyaura cross-coupling of tosylates and mesylates, spatially hindered position, 14-arylmorphinan, opioid receptor binding affinity, microwave activation

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Letters in Organic Chemistry

Title: Suzuki-Miyaura Cross-Coupling Reaction in the Functionalization of the C Ring of Morphinans

Volume: 4 Issue: 2

Author(s): Attila Sipos and Sandor Berenyi

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Keywords: Suzuki-Miyaura cross-coupling of tosylates and mesylates, spatially hindered position, 14-arylmorphinan, opioid receptor binding affinity, microwave activation

Abstract: New methods have been developed for the functionalization of the non-aromatic C ring of morphinans with Suzuki-Miyaura cross-coupling of sulfonates and bromides.

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Sipos Attila and Berenyi Sandor, Suzuki-Miyaura Cross-Coupling Reaction in the Functionalization of the C Ring of Morphinans, Letters in Organic Chemistry 2007; 4 (2) . https://dx.doi.org/10.2174/157017807780414145