Function and Molecular Mechanism of Tumor-Targeted Peptides for Delivering Therapeutic Genes and Chemical Drugs

Title: Function and Molecular Mechanism of Tumor-Targeted Peptides for Delivering Therapeutic Genes and Chemical Drugs

Volume: 6 Issue: 7

Author(s): Ryan Craig and Shulin Li

Affiliation:

Keywords: Peptide, tumor-targeting, tumor vessel, gene therapy, gene delivery, drug delivery, adhesion molecule, phage display

Abstract: Tumor-targeted chemo- or gene-therapies is a new form of treatment which provides the benefits ofreducing systemic toxicity, increasing the tolerance, and enhancing therapeutic efficacy. This review willdiscuss the discovery, function, application, and mechanism by which the short peptides (5-9) work for tumor-targeted gene or drug delivery.

Cite this article as:

Craig Ryan and Li Shulin, Function and Molecular Mechanism of Tumor-Targeted Peptides for Delivering Therapeutic Genes and Chemical Drugs, Mini-Reviews in Medicinal Chemistry 2006; 6 (7) . https://dx.doi.org/10.2174/138955706777698615